Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336215 | 0.97 | CXCR4 (0.41) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL20853809 | 0.97 | CXCR4 (0.41) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL9118993 | 0.94 | CXCR4 (0.44) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL948605 | 0.94 | CXCR4 (0.39) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL10316738 | 0.91 | CXCR4 (0.41) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL21974068 | 0.91 | CXCR4 (0.41) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL6320299 | 0.88 | ALDH1A1 (0.44) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL2517620 | 0.88 | CXCR4 (0.50) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL336034 | 0.88 | CXCR4 (0.50) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL7223038 | 0.87 | CXCR4 (0.35) | CXCR4SMN1; SMN2ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067201-A1 | Substituted 1,4,8,11-tetraazabicyclo(6.6.2)hexadecane manganese (II) complexes; imaging vascular or nephric tissue | THE PROCTER & GAMBLE COMPANY | 2004-04-08 | — | — | US | claimed |
| US-20020119101-A1 | MRI image enhancement compositions | THE PROCTER & GAMBLE COMPANY | 2002-08-29 | — | — | US | claimed |
| US-20040067201-A1 | Substituted 1,4,8,11-tetraazabicyclo(6.6.2)hexadecane manganese (II) complexes; imaging vascular or nephric tissue | THE PROCTER & GAMBLE COMPANY | 2004-04-08 | — | — | US | disclosed |
| US-20020119101-A1 | MRI image enhancement compositions | THE PROCTER & GAMBLE COMPANY | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067201-A1 | Substituted 1,4,8,11-tetraazabicyclo(6.6.2)hexadecane manganese (II) complexes; imaging vascular or nephric tissue | PKD1, SLC10A1, TFRC | CXCR4 1195/4885SMN1; SMN2 97/4885ALDH1A1 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.