Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 17/20 | 0.41 |
| ▸ | METAP2 | P50579 | 9/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861628 | 0.97 | METAP1 (0.42) | CYP1A2CYP2D6METAP1METAP2LMNA | |
| Hydrochloric Acid SCHEMBL6861864 | 0.86 | KDM4E (0.32) | CYP2D6METAP1LMNA | |
| SCHEMBL6866116 | 0.84 | METAP1 (0.33) | CYP2D6METAP1DRD2LMNA | |
| SCHEMBL6861598 | 0.84 | METAP2 (0.30) | METAP1METAP2 | |
| SCHEMBL6866255 | 0.83 | METAP1 (0.43) | METAP1METAP2 | |
| SCHEMBL6870942 | 0.83 | TLR8 (0.36) | METAP1METAP2 | |
| SCHEMBL6865853 | 0.83 | DYRK3 (0.30) | — | |
| SCHEMBL6869698 | 0.82 | CYP2D6 (0.44) | CYP1A2CYP2D6METAP1METAP2DRD2 | |
| SCHEMBL6867898 | 0.81 | METAP2 (0.31) | METAP1METAP2 | |
| SCHEMBL6865777 | 0.80 | POLB (0.38) | METAP1METAP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091957-B1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6395732-B1 | BACTERICIDES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-1091957-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999061439-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |