Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993599 | 0.78 | CYP2A6 (0.58) | EGLN2LOXL2CYP2A6MAOBKMT2A | |
| SCHEMBL4694668 | 0.78 | GRM5 (0.46) | EGLN2LOXL2CYP2A6KDM4EMAOB | |
| SCHEMBL395539 | 0.75 | CA2 (0.52) | LOXL2CYP2A6KDRSAE1UBA2 | |
| SCHEMBL5882916 | 0.75 | F7 (0.41) | EGLN2SAE1UBA2KDM4EMEN1 | |
| SCHEMBL20698865 | 0.74 | GRM5 (0.46) | EGLN2LOXL2CYP2A6KDM4EMAOB | |
| SCHEMBL21042121 | 0.73 | SAE1 (0.53) | LOXL2CYP2A6KDRSAE1UBA2 | |
| SCHEMBL29470433 | 0.73 | CSNK1D (0.61) | GSK3BMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4124112 | 0.73 | SAE1 (0.69) | KDRSAE1UBA2KDM4EMEN1 | |
| SCHEMBL12736265 | 0.73 | CYP2A6 (0.52) | EGLN2LOXL2CYP2A6MAOBMAPT | |
| SCHEMBL5612584 | 0.73 | ALDH1A1 (0.52) | CYP2A6KDRGSK3BABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-B1 | PHENYLGLYCINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-25 | — | — | EP | disclosed |