SCHEMBL6862020

SCHEMBL6862020

C#CCN1C(=O)COc2cc(F)c(-n3nc4c(c3Cl)CCCC4)cc21

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
EGFR P00533 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835748 0.87 RORC (0.37) POLB
SCHEMBL9834803 0.85 MEN1 (0.35) RAB9AMEN1KMT2ANPSR1POLB
SCHEMBL9836750 0.81
SCHEMBL9686482 0.81 BRD4 (0.46) MEN1KMT2ANPSR1
SCHEMBL9504131 0.79 CYP11B2 (0.36) EGFRPOLB
SCHEMBL9642417 0.79
Flumioxazin SCHEMBL29539500 0.79 GRM1 (0.37)
Flumioxazin SCHEMBL39699 0.79 GRM1 (0.37)
Flumioxazin SCHEMBL29088353 0.78 GRM1 (0.37)
SCHEMBL10590038 0.78 PTAFR (0.34) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304935-B1 TETRAHYDROINDAZOLYL-BENZOXAZINES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-30 EP claimed
US-4877444-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-10-31 US claimed
EP-0304935-A1 Tetrahydroindazolyl-benzoxazines, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-03-01 EP claimed
EP-0646314-B1 Sustained release pesticidal or plant growth regulating composition SUMITOMO CHEMICAL CO (JP) 2004-08-11 EP disclosed
US-5977023-A USING AQUEOUS SALT SOLUTION TO PRECIPITATE ALGINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-02 US disclosed
EP-0480679-B1 Pesticidal composition SUMITOMO CHEMICAL CO (JP) 1996-09-18 EP disclosed
EP-0646314-A1 Sustained release pesticidal or plant growth regulating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-05 EP disclosed
EP-0565354-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-10-13 EP disclosed
US-5232701-A Improvement in dispersibility in water and diffusion ability; storage stability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US disclosed
EP-0544518-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-02 EP disclosed
EP-0488660-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-03 EP disclosed
EP-0480679-A1 Pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-15 EP disclosed
EP-0304935-B1 TETRAHYDROINDAZOLYL-BENZOXAZINES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-30 EP disclosed
US-4970322-A Etherification; Herbicides SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1990-11-13 US disclosed
US-4954626-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-04 US disclosed
US-4877444-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-10-31 US disclosed
EP-0304935-A1 Tetrahydroindazolyl-benzoxazines, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-03-01 EP disclosed