Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136888 | 0.83 | PRCP (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4026574 | 0.83 | PRCP (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Formaldehyde SCHEMBL28256666 | 0.76 | MAPK1 (0.36) | CYP2D6CYP3A4MEN1KMT2ADRD1 | |
| SCHEMBL7629928 | 0.76 | SMN1; SMN2 (0.49) | KMT2A | |
| Water SCHEMBL28258294 | 0.76 | TSHR (0.35) | CYP2D6CYP3A4MEN1KMT2ADRD1 | |
| SCHEMBL4766983 | 0.76 | ALDH1A1 (0.40) | CYP2D6CYP3A4MEN1KMT2ADRD1 | |
| SCHEMBL15546633 | 0.75 | CYP2D6 (0.35) | CYP2D6CYP3A4MEN1KMT2ADRD1 | |
| SCHEMBL31121199 | 0.75 | PNMT (0.43) | PNMTCYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL6589787 | 0.74 | TSHR (0.41) | CYP2D6CYP3A4MEN1KMT2ADRD1 | |
| SCHEMBL27456289 | 0.73 | SLC6A2 (0.40) | CYP2D6CYP3A4MEN1KMT2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008548-A | Methods for modulating bile acid homeostasis and treating bile acid disorders and diseases | NGM BIOPHARMACEUTICALS INC | 2015-10-28 | — | — | CN | disclosed |
| US-20040248189-A1 | Method of making a library of phylogenetically related sequences | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-09 | — | — | US | disclosed |