SCHEMBL6862207

SCHEMBL6862207

NCCC[N]C(=O)[C@H](N)CCCN

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.47
DPP7 Q9UHL4 6/20 0.38
DPP4 P27487 3/20 0.38
NOS2 P35228 5/20 0.37
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 2/20 0.37
TSHR P16473 2/20 0.37
GLA P06280 1/20 0.37
NFKB1 P19838 1/20 0.37
APEX1 P27695 1/20 0.37
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
CPB2 Q96IY4 1/20 0.35
NOS1 P29475 4/20 0.35
NOS3 P29474 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP3A4 P08684 1/20 0.34
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5499164 1.00 GSR (0.47) GSRDPP7DPP4NOS2CYP2C19
SCHEMBL6431464 1.00 GSR (0.47) GSRDPP7DPP4NOS2CYP2C19
SCHEMBL5501937 0.94 GSR (0.55) GSRDPP7DPP4NOS2CYP2C19
SCHEMBL5497619 0.92 GSR (0.42) GSRDPP7DPP4NOS2CYP2C19
SCHEMBL5497576 0.85 GSR (0.39) GSRNOS2CYP2C19CYP1A2TSHR
SCHEMBL5497784 0.81 GNAI3 (0.58) GSRDPP7DPP8DPP9NOS1
SCHEMBL5497774 0.81 GNAI3 (0.58) GSRDPP7DPP8DPP9NOS1
SCHEMBL18739868 0.78 GSR (0.50) GSRDPP7DPP4NOS2CYP2C19
SCHEMBL5502052 0.78 GNAI3 (0.60) GSRDPP7DPP8DPP9NOS1
SCHEMBL5502056 0.78 GNAI3 (0.60) GSRDPP7DPP8DPP9NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251827-B1 NASALLY ADMINISTRABLE ANTIFUNGAL CYCLIC PEPTIDE COMPOSITIONS BASILEA PHARMACEUTICA AG (CH) 2004-05-26 EP disclosed
EP-1251827-A2 NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS Basilea Pharmaceutica AG (CH) 2002-10-30 EP disclosed
US-20010038824-A1 Intranasal cyclic peptide formulations BASILEA PHARMACEUTICA AG (CH) 2001-11-08 US disclosed
WO-2001052894-A2 NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS BASILEA PHARMACEUTICA AG (CH) 2001-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010038824-A1 Intranasal cyclic peptide formulations VIP, NPPA, SSTR5 GSR 4171/4885DPP7 1876/4885DPP4 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.