Pentane

Pentane

SCHEMBL6862649

CCC(F)(F)C(F)(F)F.CCCCC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.44
FAAH O00519 9/20 0.33
THRB P10828 1/20 0.33
CES1 P23141 10/20 0.32
CES2 O00748 4/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL6860855 0.94 TSHR (0.41) TSHRLMNAFAAHTHRBCES1
SCHEMBL32816 0.87
SCHEMBL6536228 0.87
Fluoromethane SCHEMBL18282340 0.83 TSHR (0.31) TSHR
Pentane SCHEMBL28746066 0.75 TSHR (0.64) TSHRLMNAFAAHTHRBCES1
SCHEMBL17136266 0.75 TSHR (0.35) TSHRLMNAFAAHTHRBCES1
SCHEMBL4199840 0.75
SCHEMBL1221382 0.75 TSHR (0.35) TSHRLMNAFAAHTHRBCES1
Pentane SCHEMBL3463399 0.73 TSHR (0.50) TSHRLMNAFAAHTHRBCES1
SCHEMBL9974576 0.73 CES2 (0.43) TSHRFAAHTHRBCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425075-A1 AZEOTROPE-LIKE COMPOSITIONS OF PENTAFLUOROBUTANE Honeywell International Inc. (US) 2004-06-09 EP disclosed
WO-2002098528-A1 AZEOTROPE-LIKE COMPOSITIONS OF PENTAFLUOROBUTANE HONEYWELL INTERNATIONAL, INC. (US) 2002-12-12 WO disclosed