Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 3/20 | 0.33 |
| ▸ | WNT3 | P56703 | 2/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863244 | 0.93 | S1PR2 (0.40) | S1PR2KDRMTORP2RX7CXCR3 | |
| SCHEMBL6863132 | 0.93 | S1PR2 (0.40) | S1PR2KDRMTORP2RX7CXCR3 | |
| SCHEMBL6863176 | 0.89 | S1PR2 (0.40) | S1PR2KDRCXCR3CCR3CYP2D6 | |
| SCHEMBL6863044 | 0.82 | S1PR2 (0.41) | S1PR2P2RX7CCR4WNT3SFRP1 | |
| SCHEMBL6863109 | 0.82 | S1PR2 (0.41) | S1PR2P2RX7CCR4WNT3SFRP1 | |
| SCHEMBL12005722 | 0.82 | S1PR2 (0.41) | S1PR2P2RX7CCR4WNT3SFRP1 | |
| SCHEMBL8374023 | 0.81 | EPHX2 (0.41) | KDRP2RX7CXCR3WNT3SFRP1 | |
| SCHEMBL6863253 | 0.81 | CCR3 (0.38) | CCR3CCR4 | |
| SCHEMBL17860811 | 0.79 | EPHX2 (0.42) | KDRP2RX7CXCR3WNT3SFRP1 | |
| SCHEMBL15353984 | 0.79 | EPHX2 (0.42) | KDRP2RX7CXCR3WNT3SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |