Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863176 | 0.91 | S1PR2 (0.40) | CCR3MAPT | |
| SCHEMBL6863244 | 0.85 | S1PR2 (0.40) | CCR3MAPT | |
| SCHEMBL6863132 | 0.85 | S1PR2 (0.40) | CCR3MAPT | |
| SCHEMBL6863172 | 0.81 | S1PR2 (0.37) | CCR3CCR4 | |
| SCHEMBL6863225 | 0.80 | EPHX2 (0.47) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6863181 | 0.79 | S1PR2 (0.41) | CCR4 | |
| SCHEMBL6863109 | 0.73 | S1PR2 (0.41) | LMNACCR4 | |
| SCHEMBL6863044 | 0.73 | S1PR2 (0.41) | LMNACCR4 | |
| SCHEMBL12005722 | 0.73 | S1PR2 (0.41) | LMNACCR4 | |
| SCHEMBL6863248 | 0.72 | CXCR3 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |