Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.62 |
| ▸ | F12 | P00748 | 12/20 | 0.43 |
| ▸ | F2 | P00734 | 10/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867942 | 0.92 | ADORA2A (0.71) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6869818 | 0.84 | ADORA2A (0.70) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6870369 | 0.82 | ADORA2A (0.61) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6870136 | 0.82 | ADORA2A (0.61) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6863310 | 0.81 | ADORA2A (0.64) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6863344 | 0.81 | ADORA2A (0.63) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6869917 | 0.81 | ADORA2A (0.58) | ADORA2AF12F2 | |
| SCHEMBL6867379 | 0.81 | ADORA2A (0.66) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6871898 | 0.80 | ADORA2A (0.62) | ADORA2AF12F2PLAUPLG | |
| SCHEMBL6868483 | 0.79 | ADORA2A (0.64) | ADORA2AF12F2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |