⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692524 | 0.78 | — | — | |
| SCHEMBL28444613 | 0.77 | — | — | |
| SCHEMBL6410731 | 0.76 | — | — | |
| SCHEMBL9698656 | 0.76 | — | — | |
| SCHEMBL1592496 | 0.76 | — | — | |
| SCHEMBL4694810 | 0.74 | — | — | |
| SCHEMBL630894 | 0.73 | — | — | |
| SCHEMBL2011845 | 0.73 | — | — | |
| SCHEMBL311015 | 0.72 | — | — | |
| SCHEMBL856758 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452152-A | 1,3- dioxoisoindolin benzamide compound and application thereof | INST MATERIA MEDICA CAMS | 2019-11-15 | — | — | CN | claimed |
| CN-109071782-A | Use of donor-acceptor polymers based on fluorobenzooxadiazoles in electronics and photonics | 香港科技大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108948011-A | A kind of preparation method of the sandy star in pula | 华南农业大学 | 2018-12-07 | — | — | CN | claimed |
| CN-105669520-A | Tryptophan basic skeleton-containing o-phenylenediamine selective histone deacetylase inhibitor and its preparation method and use | 山东大学 | 2016-06-15 | — | — | CN | claimed |
| CN-104407066-A | Analysis method of retigabine related substances | ANHUI WANBANG MEDICAL TECHNOLOGY CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-116348114-A | Thiobenzimidazole derivatives or pharmaceutically acceptable salts thereof and use thereof | 高丽大学校产学协力团 | 2023-06-27 | — | — | CN | disclosed |
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |
| US-11078189-B2 | Pharmaceutical compounds | ReViral Limited (GB) | 2021-08-03 | — | — | US | disclosed |
| CN-107935858-B | Preparation method of 5-fluoro-2-nitrophenol | 利尔化学股份有限公司 | 2020-09-08 | — | — | CN | disclosed |
| US-20200172515-A1 | PHARMACEUTICAL COMPOUNDS | SILICON VALLEY BANK | 2020-06-04 | — | — | US | disclosed |
| CN-110452152-A | 1,3- dioxoisoindolin benzamide compound and application thereof | INST MATERIA MEDICA CAMS | 2019-11-15 | — | — | CN | disclosed |
| CN-110446699-A | 2(1H) -quinolinone derivatives | TAISHO PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-105307657-A | Heteroaryl compounds and uses thereof | CELGENE AVILOMICS RES INC | 2016-02-03 | — | — | CN | disclosed |
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |
| CN-104407066-A | Analysis method of retigabine related substances | ANHUI WANBANG MEDICAL TECHNOLOGY CO LTD | 2015-03-11 | — | — | CN | disclosed |
| CN-103004799-B | Application of benzofuroxan derivative to resisting plant pathogenic fungi | UNIV SOOCHOW | 2014-12-31 | — | — | CN | disclosed |
| CN-104024248-A | SERINE/THREONINE PAK1 INHIBITORS | HOFFMANN LA ROCHE | 2014-09-03 | — | — | CN | disclosed |
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |
| EP-1379522-A1 | DIHYDRO-BENZO(b)(1,4)DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083665-A1 | DIHYDRO-BENZO[b][1,4]DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-24 | — | — | WO | disclosed |