Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 16/20 | 0.47 |
| ▸ | NMT1 | P30419 | 16/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472650 | 0.80 | NMT2 (0.71) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL3472647 | 0.79 | NMT2 (0.70) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6869324 | 0.77 | NMT2 (0.49) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL3473958 | 0.74 | NMT2 (0.52) | NMT2NMT1 | |
| SCHEMBL7042865 | 0.70 | NMT2 (0.77) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL3918141 | 0.68 | KCNA3 (0.60) | — | |
| Hydrochloric Acid SCHEMBL5302289 | 0.67 | ABCG2 (0.36) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL3470200 | 0.66 | NMT2 (0.36) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL7448429 | 0.65 | MTNR1A (0.67) | — | |
| Hydrochloric Acid SCHEMBL6872183 | 0.65 | NMT2 (0.77) | NMT2NMT1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |