SCHEMBL6863712

SCHEMBL6863712

[SiH3]OCCN1CCCCC1OC(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.44
CHRM2 P08172 3/20 0.43
ADRA2A P08913 3/20 0.43
CHRM1 P11229 3/20 0.43
DRD1 P21728 3/20 0.43
SLC6A2 P23975 3/20 0.43
ADRA1A P35348 3/20 0.43
OPRM1 P35372 3/20 0.43
DRD3 P35462 3/20 0.43
SLC6A3 Q01959 3/20 0.43
KCNH2 Q12809 3/20 0.43
HTR1A P08908 2/20 0.43
CYP2D6 P10635 2/20 0.43
HRH3 Q9Y5N1 1/20 0.43
MAPK1 P28482 1/20 0.43
SLC6A4 P31645 2/20 0.40
CHRNA7 P36544 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
DRD2 P14416 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7006987 0.82 CHRM2 (0.43) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938226 0.78 HRH3 (0.40) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938542 0.78 HRH3 (0.49) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938621 0.78 SIGMAR1 (0.41) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938361 0.78 GBA1 (0.41) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938514 0.78 HRH3 (0.42) HRH3
SCHEMBL8938201 0.78 HRH3 (0.53) CHRM2ADRA2ACHRM1DRD1SLC6A2
SCHEMBL8938558 0.77 HRH3 (0.52) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938454 0.77 HRH3 (0.54) SIGMAR1CHRM2ADRA2ACHRM1DRD1
SCHEMBL8938460 0.76 HRH3 (0.58) SIGMAR1KCNH2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6797444-B2 A PROTECTIVE LAYER CONTAINING A COUPLING FLUOROPOLYMER PARTICLES DISPERSED IN A COPOLYMER HAVING A FLUORINE ATOM-CONTAINING SILOXANE ADDITION-CONDENSATION PRODUCT IN A SIDE CHAIN; NONABRASIVE, HARDENING KONICA CORPORATION (JP) 2004-09-28 US disclosed
US-20030134209-A1 Electrophotographic photoreceptor and production method of the same KONICA CORPORATION (JP) 2003-07-17 US disclosed
US-6569586-B2 Comprises photosensitive layer and resin layer including organic polymer, siloxane component, and charge transfer component; durability KONICA CORPORATION (JP) 2003-05-27 US disclosed
US-20020076631-A1 Photoreceptor for forming electrostatic latent image KONICA CORPORATION (JP) 2002-06-20 US disclosed