SCHEMBL6864020

SCHEMBL6864020

c1ccc(CN(CCCN(CCN(Cc2ccccn2)Cc2ccccn2)Cc2ccccn2)CCN(Cc2ccccn2)Cc2ccccn2)nc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.85
SMN1; SMN2 Q16637 1/20 0.85
LIN28A Q9H9Z2 1/20 0.85
TDP1 Q9NUW8 1/20 0.85
TERT O14746 1/20 0.52
CXCR4 P61073 2/20 0.46
KCNA5 P22460 1/20 0.46
KMT2A Q03164 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CHRM2 P08172 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107996 0.96 MAPT (0.84) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL29427509 0.92 TDP1 (1.00) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL231092 0.92 TDP1 (1.00) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL10609540 0.90 TDP1 (0.96) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL846457 0.90 TDP1 (0.73) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL16590475 0.87 TDP1 (0.70) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL825403 0.87 TDP1 (0.69) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL1332466 0.87 TDP1 (0.69) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL825181 0.87 TDP1 (0.69) MAPTSMN1; SMN2LIN28ATDP1TERT
SCHEMBL5562384 0.85 TDP1 (0.67) MAPTSMN1; SMN2LIN28ATDP1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1008645-B1 Detergent bleaching compositions UNILEVER PLC (GB) 2004-07-21 EP disclosed
EP-1001009-B1 Bleach and oxidation catalyst UNILEVER PLC (GB) 2003-09-03 EP disclosed
US-6165963-A Detergent bleaching composition comprising pentadentate ligand derivatives UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2000-12-26 US disclosed
US-6140294-A OXIDATION CATALYST COMPRISING AN IRON, MANGANESE OR COPPER COMPLEX INCLUDING A SPECIFIED PENTADENTATE NITROGEN-CONTAINING LIGAND UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2000-10-31 US disclosed
EP-1008645-A1 Detergent bleaching compositions UNILEVER PLC (GB) 2000-06-14 EP disclosed
EP-1001009-A1 Bleach and oxidation catalyst UNILEVER PLC (GB) 2000-05-17 EP disclosed
US-6022490-A FOR ACTIVATING PEROXY BLEACH LEVER BROTHERS COMPANY (US) 2000-02-08 US disclosed
EP-0906402-A1 BLEACH ACTIVATION UNILEVER N.V. (NL) 1999-04-07 EP disclosed
WO-1997048787-A1 BLEACH ACTIVATION UNILEVER N.V. (NL) 1997-12-24 WO disclosed