Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.60 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864929 | 0.90 | GPR52 (0.70) | GPR52 | |
| SCHEMBL6866106 | 0.87 | GPR52 (0.70) | GPR52PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13506369 | 0.86 | GPR52 (0.55) | GPR52PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6864660 | 0.84 | GPR52 (0.66) | GPR52 | |
| SCHEMBL6863905 | 0.84 | GPR52 (0.60) | GPR52SCD | |
| SCHEMBL13506176 | 0.82 | GPR52 (0.69) | GPR52SCD | |
| SCHEMBL6864502 | 0.82 | GPR52 (0.81) | GPR52SCD | |
| SCHEMBL13505990 | 0.82 | GPR52 (0.54) | GPR52PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6864620 | 0.81 | GPR52 (0.81) | GPR52 | |
| SCHEMBL6863098 | 0.81 | GPR52 (0.65) | GPR52SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |