SCHEMBL6864660

SCHEMBL6864660

Cc1cc(C(=O)NCC(N)=O)nn1-c1cccc2cc(Cc3cccc(C(F)(F)F)c3)sc12

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 15/20 0.66
NPY5R Q15761 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6865079 0.90 GPR52 (0.80) GPR52NPY5R
SCHEMBL6864973 0.89 GPR52 (0.81) GPR52
SCHEMBL6864385 0.89 GPR52 (0.62) GPR52
SCHEMBL6863851 0.86 GPR52 (0.83) GPR52
SCHEMBL13505934 0.86 GPR52 (0.64) GPR52NPY5R
SCHEMBL13506490 0.86 GPR52 (0.83) GPR52
SCHEMBL6864620 0.85 GPR52 (0.81) GPR52
SCHEMBL6863098 0.85 GPR52 (0.65) GPR52
SCHEMBL6864077 0.84 GPR52 (0.60) GPR52
SCHEMBL13506275 0.83 GPR52 (0.61) GPR52NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518054-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2012-10-31 EP disclosed
WO-2011078360-A1 AMIDE COMPOUND 武田薬品工業株式会社 (JP) 2011-06-30 WO disclosed