Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | PGK2 | P07205 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 2/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dexfosfoserine SCHEMBL18301530 | 0.88 | GRM8 (0.62) | ALOX15BLMPMP22KMT2APGK1 | |
| Dexfosfoserine SCHEMBL20798048 | 0.86 | PGK1 (0.59) | PGK1PGK2PGD | |
| Dexfosfoserine SCHEMBL6847 | 0.86 | PGK1 (0.59) | PGK1PGK2PGD | |
| Dexfosfoserine SCHEMBL6846 | 0.86 | PGK1 (0.59) | PGK1PGK2PGD | |
| Dexfosfoserine SCHEMBL29427835 | 0.86 | PGK1 (0.59) | PGK1PGK2PGD | |
| Glutamine SCHEMBL27986532 | 0.84 | ALOX15 (0.70) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL2351128 | 0.84 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL2351130 | 0.84 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL27986533 | 0.84 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGRM8 | |
| Dexfosfoserine SCHEMBL4285884 | 0.84 | PGK1 (0.57) | PGK1PGK2PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803203-B1 | PROTEIN KINASES; FOR MONITORING IN VITRO ACTIVITY IN EUKARYOTIC CELLS; DRUG SCREENING; KITS | BROOKHAVEN SCIENCE ASSOCIATES | 2004-10-12 | — | — | US | disclosed |