Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6852493 | 0.99 | EPHX1 (0.33) | HPGDEPHX1LMNAGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5854437 | 0.81 | HPGD (0.38) | HPGDLMNAGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5853180 | 0.80 | HPGD (0.40) | HPGDLMNAGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5855531 | 0.80 | HPGD (0.40) | HPGDLMNAGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6843489 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6843297 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6846579 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5852722 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5855617 | 0.76 | NAPRT (0.30) | — | |
| Hydrochloric Acid SCHEMBL5855109 | 0.74 | GAA (0.33) | HPGDGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |