Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5855531 | 0.99 | HPGD (0.40) | HPGDRECQLLMNAP2RX7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853180 | 0.99 | HPGD (0.40) | HPGDRECQLLMNAP2RX7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5855617 | 0.83 | NAPRT (0.30) | HSD17B10 | |
| Hydrochloric Acid SCHEMBL5852581 | 0.81 | SMN1; SMN2 (0.34) | LMNAP2RX7NPSR1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL5853817 | 0.81 | L3MBTL1 (0.46) | HPGDLMNAALDH1A1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL5853650 | 0.81 | SMN1; SMN2 (0.33) | HPGDLMNAALDH1A1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL6864359 | 0.81 | HPGD (0.32) | HPGDLMNANPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL5855109 | 0.81 | GAA (0.33) | HPGDRECQLALDH1A1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL5854813 | 0.80 | HDAC8 (0.34) | HPGDLMNAP2RX7NPSR1NPC1 | |
| Hydrochloric Acid SCHEMBL5853512 | 0.80 | HDAC8 (0.34) | HPGDLMNAP2RX7NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |