Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 1.00 |
| ▸ | CCR1 | P32246 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13505642 | 0.87 | GPR52 (1.00) | GPR52 | |
| SCHEMBL13506787 | 0.86 | GPR52 (0.75) | GPR52CCR1NPSR1KDM4E | |
| SCHEMBL13506290 | 0.85 | GPR52 (0.73) | GPR52CCR1KDM4EMAPT | |
| SCHEMBL6865577 | 0.84 | GPR52 (1.00) | GPR52 | |
| SCHEMBL13505580 | 0.83 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864474 | 0.83 | GPR52 (0.87) | GPR52 | |
| SCHEMBL6864857 | 0.83 | GPR52 (0.87) | GPR52 | |
| SCHEMBL6864118 | 0.81 | GPR52 (0.84) | GPR52 | |
| SCHEMBL6866106 | 0.80 | GPR52 (0.70) | GPR52 | |
| SCHEMBL3198843 | 0.80 | GPR52 (0.74) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |