Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 15/20 | 1.00 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864474 | 0.93 | GPR52 (0.87) | GPR52SCD | |
| SCHEMBL6864624 | 0.92 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864620 | 0.88 | GPR52 (0.81) | GPR52 | |
| SCHEMBL13506129 | 0.86 | GPR52 (0.77) | GPR52 | |
| SCHEMBL13505878 | 0.85 | GPR52 (0.76) | GPR52 | |
| SCHEMBL13505580 | 0.85 | GPR52 (1.00) | GPR52SCD | |
| SCHEMBL13505642 | 0.85 | GPR52 (1.00) | GPR52SCD | |
| SCHEMBL13505659 | 0.85 | GPR52 (0.73) | GPR52 | |
| SCHEMBL6864360 | 0.84 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864108 | 0.84 | GPR52 (0.85) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | claimed |
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |