Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | MELK | Q14680 | 1/20 | 0.47 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825325 | 0.95 | ALDH1A1 (0.65) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28877491 | 0.90 | ALDH1A1 (0.81) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29349435 | 0.89 | JAK2 (0.54) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL65699 | 0.89 | JAK2 (0.54) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL16107486 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL9627127 | 0.86 | JAK2 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL11698588 | 0.86 | JAK2 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL11277860 | 0.86 | JAK2 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL2638226 | 0.86 | JAK2 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Fluoride SCHEMBL11274176 | 0.86 | JAK2 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6805718-B2 | USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME | NOVOZYMES A/S (DK) | 2004-10-19 | — | — | US | claimed |