Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863606 | 0.89 | GPR52 (0.67) | GPR52ALDH1A1PPARASMN1; SMN2CHRM4 | |
| SCHEMBL6864668 | 0.89 | GPR52 (0.51) | GPR52ALDH1A1GAANPC1PPARA | |
| SCHEMBL13505716 | 0.86 | SMN1; SMN2 (0.57) | GPR52ALDH1A1GAANPC1PPARA | |
| SCHEMBL6864185 | 0.83 | GPR52 (0.69) | GPR52ALDH1A1GAANPC1PPARA | |
| SCHEMBL13505788 | 0.83 | MAPT (0.51) | GPR52ALDH1A1NPC1SMN1; SMN2MEN1 | |
| SCHEMBL3217725 | 0.80 | GPR52 (0.79) | GPR52GAAMEN1KMT2A | |
| SCHEMBL6864277 | 0.80 | GPR52 (0.53) | GPR52ALDH1A1GAANPC1PPARA | |
| SCHEMBL6864254 | 0.77 | GPR52 (0.55) | GPR52NPC1SMN1; SMN2MAPT | |
| SCHEMBL3206518 | 0.73 | GPR52 (0.78) | GPR52ALDH1A1 | |
| SCHEMBL1848355 | 0.73 | GPR52 (0.78) | GPR52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |