SCHEMBL6864675

SCHEMBL6864675

Cc1nc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)n(C)c1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13506058 0.92 GPR52 (0.55) GPR52
SCHEMBL13506797 0.89 GPR52 (0.66) GPR52
SCHEMBL13505393 0.89 GPR52 (0.53) GPR52
SCHEMBL6864852 0.88 GPR52 (0.58) GPR52
SCHEMBL6865325 0.87 GPR52 (0.55) GPR52
SCHEMBL13505894 0.83 GPR52 (0.55) GPR52
SCHEMBL6863562 0.82 GPR52 (0.56) GPR52
SCHEMBL6864259 0.81 GPR52 (0.66) GPR52
SCHEMBL13505766 0.80 GPR52 (0.57) GPR52
SCHEMBL13506211 0.80 GPR52 (0.53) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518054-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2012-10-31 EP disclosed
WO-2011078360-A1 AMIDE COMPOUND 武田薬品工業株式会社 (JP) 2011-06-30 WO disclosed