Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937404 | 0.91 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1CASP2 | |
| SCHEMBL6864354 | 0.86 | — | — | |
| SCHEMBL1416032 | 0.84 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2ACHEMAPT | |
| SCHEMBL6863656 | 0.84 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2EPHX1ACHEMMP2 | |
| SCHEMBL1395631 | 0.81 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2EPHX1ACHEMMP2 | |
| SCHEMBL1395670 | 0.81 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2EPHX1ACHEMMP2 | |
| SCHEMBL4870992 | 0.81 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2EPHX1ACHEMMP2 | |
| SCHEMBL4894334 | 0.79 | — | — | |
| SCHEMBL1416228 | 0.79 | — | — | |
| SCHEMBL486681 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034326-B1 | CHIRAL POLYSILOXANES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Bayer, Ernst, Prof. Dr. (DE) | 1984-07-25 | — | — | EP | claimed |
| US-4387206-A | CHROMATOGRAPHY | BAYER ERNST (DE) | 1983-06-07 | — | — | US | claimed |
| US-6797699-B1 | EXEMPLIFIED BY N'-L-ARGINYLSPERMIDINE | UNIVERSITY OF SOUTHAMPTON (GB) | 2004-09-28 | — | — | US | disclosed |
| EP-1040096-B1 | NEUROPROTECTIVE AGENTS | UNIV SOUTHAMPTON (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-6150351-A | ADMINISTERING AN EFFECTIVE AMOUNT OF THE CEPHEM COMPOUND TO A PATIENT SUFFERING FROM DISEASES CAUSED BY HELICOBACTER PYLORI | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0034326-B1 | CHIRAL POLYSILOXANES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Bayer, Ernst, Prof. Dr. (DE) | 1984-07-25 | — | — | EP | disclosed |