SCHEMBL937404

SCHEMBL937404

CC[CH]C(=O)NCCCCCCCCCCCCCCCCCC

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.66
ZDHHC2 Q9UIJ5 3/20 0.66
EPHX1 P07099 10/20 0.59
CASP2 P42575 1/20 0.53
EGFR P00533 1/20 0.50
NAAA Q02083 1/20 0.50
FAAH O00519 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6864828 0.91 ZDHHC20 (0.53) ZDHHC20ZDHHC2EPHX1CASP2
SCHEMBL28179342 0.86 ZDHHC20 (0.63) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL28969054 0.84 ZDHHC20 (0.61) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL1700944 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL5362502 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL2534467 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL6131120 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL1700721 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL444526 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR
SCHEMBL1700805 0.83 ZDHHC20 (0.70) ZDHHC20ZDHHC2EPHX1CASP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2482789-B1 HAIR TREATMENT COMPOSITION COMPRISING POLYOXYALKYLENE ALKYL ETHER KAO CORP (JP) 2018-04-25 EP disclosed
EP-1803434-B1 Hair dye composition KAO CORP (JP) 2015-12-09 EP disclosed
EP-1649847-B1 METHOD FOR GROOMING HAIR KAO CORP (JP) 2013-09-18 EP disclosed
US-8512686-B2 Hair grooming preparation KAO CORPORATION (JP) 2013-08-20 US disclosed
EP-1894556-B1 Aqueous hair cosmetic composition KAO CORP (JP) 2013-04-17 EP disclosed
US-8349024-B2 Hair treatment composition KAO CORPORATION (JP) 2013-01-08 US disclosed
EP-2482789-A2 HAIR TREATMENT COMPOSITION COMPRISING POLYOXYALKYLENE ALKYL ETHER Kao Corporation (JP) 2012-08-08 EP disclosed
EP-1656926-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2012-06-06 EP disclosed
EP-1547574-B2 Hair cosmetic compositions KAO CORP (JP) 2012-05-30 EP disclosed
US-20120128615-A1 HAIR TREATMENT COMPOSITION KAO CORPORATION (JP) 2012-05-24 US disclosed
US-20080050330-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-02-28 US disclosed
US-20070157399-A1 HAIR DYE COMPOSITION KAO CORPORATION (JP) 2007-07-12 US disclosed
EP-1547574-B1 Hair cosmetic compositions KAO CORP (JP) 2007-07-11 EP disclosed
EP-1803434-A1 Hair dye composition Kao Corporation (JP) 2007-07-04 EP disclosed
US-20060198807-A1 Hair grooming preparation KAO CORPORATION (JP) 2006-09-07 US disclosed
US-20060165628-A1 Hair care product KAO CORPORATION (JP) 2006-07-27 US disclosed
EP-1656926-A1 HAIR CARE PRODUCT Kao Corporation (JP) 2006-05-17 EP disclosed
EP-1649847-A1 HAIR GROOMING PREPARATION Kao Corporation (JP) 2006-04-26 EP disclosed
US-20050142091-A1 A rinse-off type hair cosmetic used before or after shampooing colored hair; higher alcohol of c12-c28, a quaternaryammonium or tertiaryamine compound, a polyhydric alcohol and dimethylpolysiloxane; discoloration inhibition KAO CORPORATION (JP) 2005-06-30 US disclosed
EP-1547574-A1 Hair cosmetic compositions Kao Corporation (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060198807-A1 Hair grooming preparation H1-0, EBP, POLR1C ZDHHC20 247/4885ZDHHC2 333/4885EPHX1 2803/4885
US-20070157399-A1 HAIR DYE COMPOSITION SMOX, AOC3, TYR ZDHHC20 769/4885ZDHHC2 1120/4885EPHX1 1922/4885
US-20080050330-A1 AQUEOUS HAIR COSMETIC COMPOSITION SHH, POLR1C, CUTA ZDHHC20 605/4885ZDHHC2 1589/4885EPHX1 3757/4885
US-20060165628-A1 Hair care product CUTA, POLR1C, PLK4 ZDHHC20 1167/4885ZDHHC2 2074/4885EPHX1 4435/4885
US-20050142091-A1 A rinse-off type hair cosmetic used before or after shampooing colored hair; higher alcohol of c12-c28, a quaternaryammonium or tertiaryamine compound, a polyhydric alcohol and dimethylpolysiloxane; discoloration inhibition H1-0, TET2, H1-2 ZDHHC20 1370/4885ZDHHC2 1238/4885EPHX1 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.