Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.52 |
| ▸ | CCR6 | P51684 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169778 | 1.00 | HSP90AA1 (0.52) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| SCHEMBL5171916 | 0.96 | CCR6 (0.53) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| SCHEMBL6866491 | 0.96 | CCR6 (0.53) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| SCHEMBL5172342 | 0.92 | CCR6 (0.61) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| SCHEMBL6867945 | 0.92 | CCR6 (0.61) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1524678 | 0.91 | CCR6 (0.63) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9300503 | 0.91 | CCR6 (0.63) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1524458 | 0.91 | CCR6 (0.63) | HSP90AA1CCR6EGFRNPC1RAB9A | |
| SCHEMBL6868242 | 0.84 | HSP90AA1 (0.48) | HSP90AA1CCR6NPC1RAB9AMITF | |
| SCHEMBL5168451 | 0.84 | HSP90AA1 (0.48) | HSP90AA1CCR6NPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815443-B2 | CARBOCYCLIC OXY AMINES SUCH AS 2-BENZYLIDENE-6-DIMETHYLAMINO METHYLCYCLOHEXANONE, USED AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2004-11-09 | — | — | US | disclosed |
| US-20030220390-A1 | 5-Amino-1-pentene-3-ol substituted derivatives | GRUENENTHAL GMBH (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220390-A1 | 5-Amino-1-pentene-3-ol substituted derivatives | ALOX5, PGA5, ANXA5 | HSP90AA1 3894/4885CCR6 3774/4885EGFR 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.