Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.81 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12338697 | 0.98 | TDP1 (0.78) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL8604224 | 0.90 | TDP1 (0.70) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL29877048 | 0.90 | TDP1 (0.70) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL804309 | 0.90 | TDP1 (0.70) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL29427509 | 0.90 | TDP1 (1.00) | TDP1MAPTSMN1; SMN2LIN28ATSHR | |
| SCHEMBL231092 | 0.90 | TDP1 (1.00) | TDP1MAPTSMN1; SMN2LIN28ATSHR | |
| SCHEMBL10609540 | 0.88 | TDP1 (0.96) | TDP1MAPTSMN1; SMN2LIN28ATSHR | |
| SCHEMBL11471516 | 0.88 | TDP1 (0.62) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL13555816 | 0.88 | TDP1 (0.62) | TDP1MAPTSMN1; SMN2LIN28ADRD2 | |
| SCHEMBL29893315 | 0.87 | TDP1 (0.78) | TDP1MAPTSMN1; SMN2LIN28ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11125741-B2 | Compositions and methods for the detection of zinc | NORTHWESTERN UNIVERSITY (US) | 2021-09-21 | — | — | US | disclosed |
| EP-3497095-B1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | UNIV OSLO (NO) | 2021-07-14 | — | — | EP | disclosed |
| US-20190033299-A1 | COMPOSITIONS AND METHODS FOR THE DETECTION OF ZINC | NORTHWESTERN UNIVERSITY | 2019-01-31 | — | — | US | disclosed |
| WO-2018033719-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2018-02-22 | — | — | WO | disclosed |
| US-9897595-B2 | Compositions and methods for the detection of zinc | NORTHWESTERN UNIVERSITY (US) | 2018-02-20 | — | — | US | disclosed |
| EP-1008645-B1 | Detergent bleaching compositions | UNILEVER PLC (GB) | 2004-07-21 | — | — | EP | disclosed |
| US-6165963-A | Detergent bleaching composition comprising pentadentate ligand derivatives | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1008645-A1 | Detergent bleaching compositions | UNILEVER PLC (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-2000027975-A1 | DETERGENT BLEACHING COMPOSITION | UNILEVER PLC (GB) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11125741-B2 | Compositions and methods for the detection of zinc | SLC30A6, SLC39A3, SLC30A7 | TDP1 2876/4885MAPT 1975/4885SMN1; SMN2 1520/4885 |
| US-20190033299-A1 | COMPOSITIONS AND METHODS FOR THE DETECTION OF ZINC | SLC30A6, SLC39A3, SLC30A7 | TDP1 2876/4885MAPT 1975/4885SMN1; SMN2 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.