SCHEMBL6865015

SCHEMBL6865015

Cc1nn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c(C)c1C(N)=O

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6864693 0.93 GPR52 (0.78) GPR52
SCHEMBL13506314 0.92 GPR52 (0.77) GPR52
SCHEMBL6865119 0.90 GPR52 (0.78) GPR52
SCHEMBL6864973 0.89 GPR52 (0.81) GPR52
SCHEMBL13506224 0.89 GPR52 (0.73) GPR52
SCHEMBL6863958 0.88 GPR52 (0.59) GPR52
SCHEMBL6864650 0.87 GPR52 (0.59) GPR52
SCHEMBL6864495 0.86 GPR52 (1.00) GPR52
SCHEMBL6864662 0.85 GPR52 (0.61) GPR52
SCHEMBL6865068 0.85 GPR52 (0.57) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518054-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2012-10-31 EP disclosed
WO-2011078360-A1 AMIDE COMPOUND 武田薬品工業株式会社 (JP) 2011-06-30 WO disclosed