SCHEMBL6865068

SCHEMBL6865068

Cc1nn(-c2cccc3sc(Cc4cccc(C(F)(F)F)c4)cc23)c(C)c1C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 19/20 0.57
SCD O00767 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13505547 0.92 GPR52 (0.57) GPR52SCD
SCHEMBL6864628 0.89 GPR52 (0.62) GPR52SCD
SCHEMBL13506045 0.89 GPR52 (0.55) GPR52SCD
SCHEMBL6864796 0.86 GPR52 (0.77) GPR52
SCHEMBL6865015 0.85 GPR52 (0.76) GPR52
SCHEMBL6864650 0.85 GPR52 (0.59) GPR52
SCHEMBL6864272 0.83 GPR52 (0.50) GPR52
SCHEMBL13506492 0.81 GPR52 (0.41) GPR52
SCHEMBL6864693 0.79 GPR52 (0.78) GPR52
SCHEMBL6865232 0.79 GPR52 (0.48) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518054-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2012-10-31 EP disclosed
WO-2011078360-A1 AMIDE COMPOUND 武田薬品工業株式会社 (JP) 2011-06-30 WO disclosed