Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550410 | 0.92 | NPSR1 (0.54) | NPSR1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL6862461 | 0.92 | NPSR1 (0.54) | NPSR1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL2628180 | 0.88 | PPARG (0.53) | NPSR1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL2615858 | 0.88 | PPARG (0.53) | NPSR1TDP1MAPTALDH1A1TSHR | |
| SCHEMBL8239220 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRJAK3BTK | |
| SCHEMBL346337 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRJAK3BTK | |
| SCHEMBL29119136 | 0.85 | SIRT2 (0.59) | MAPT | |
| SCHEMBL29119131 | 0.85 | SIRT2 (0.59) | MAPT | |
| SCHEMBL20838286 | 0.84 | FOLH1 (0.57) | NPSR1TDP1MAPTMEN1KMT2A | |
| SCHEMBL20838288 | 0.84 | FOLH1 (0.57) | NPSR1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803383-B2 | UTILIZING SELECTIVE INHIBITORS OF THE BINDING OF INTEGRIN ALPHA V BETA 3 WITH MATRIX METALLOPROTEINASE 2 | THE SCRIPPS RESEARCH INSTITUTE | 2004-10-12 | — | — | US | disclosed |
| US-20030083519-A1 | Inhibition of angiognenesis and tumor growth | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083519-A1 | Inhibition of angiognenesis and tumor growth | FLT1, TEK, MKI67 | NPSR1 3128/4885TDP1 4842/4885MAPT 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.