Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 18/20 | 0.80 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864660 | 0.90 | GPR52 (0.66) | GPR52NPY5R | |
| SCHEMBL6864495 | 0.89 | GPR52 (1.00) | GPR52HTR2B | |
| SCHEMBL6865207 | 0.89 | GPR52 (0.77) | GPR52HTR2B | |
| SCHEMBL6866189 | 0.88 | GPR52 (1.00) | GPR52HTR2B | |
| SCHEMBL13505934 | 0.87 | GPR52 (0.64) | GPR52NPY5R | |
| SCHEMBL6864790 | 0.87 | GPR52 (1.00) | GPR52HTR2B | |
| SCHEMBL6864624 | 0.85 | GPR52 (1.00) | GPR52HTR2B | |
| SCHEMBL6863913 | 0.85 | GPR52 (0.86) | GPR52 | |
| SCHEMBL13506275 | 0.84 | GPR52 (0.61) | GPR52NPY5R | |
| SCHEMBL6864929 | 0.84 | GPR52 (0.70) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |