Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993463 | 0.81 | CHRNA7 (0.45) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3049706 | 0.76 | CHRNA7 (0.54) | CHRNA7PDE4BHSD17B10KDM4ENPC1 | |
| SCHEMBL14755328 | 0.76 | CHRNA7 (0.54) | CHRNA7PDE4BHSD17B10KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL28460391 | 0.75 | CHRNA7 (0.53) | CHRNA7PDE4BHSD17B10KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL30842786 | 0.75 | CHRNA7 (0.53) | CHRNA7PDE4BHSD17B10KDM4ENPC1 | |
| SCHEMBL5762667 | 0.72 | CHRNA7 (0.55) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16537757 | 0.72 | PDE4A (0.53) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16536586 | 0.72 | PDE4A (0.53) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16930321 | 0.69 | CHRNA7 (0.49) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20482814 | 0.69 | CHRNA7 (0.49) | CHRNA7PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797823-B1 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-09-28 | — | — | US | disclosed |