Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865208 | 0.81 | CHRNA7 (0.44) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16537757 | 0.73 | PDE4A (0.53) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16536586 | 0.73 | PDE4A (0.53) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5762667 | 0.73 | CHRNA7 (0.55) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1894922 | 0.72 | CHRNA7 (0.51) | CHRNA7PDE4BCTSVCTSLSRD5A1 | |
| SCHEMBL6031474 | 0.70 | EGFR (0.50) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13791570 | 0.68 | MAOB (0.62) | MAPK1HSD17B10SMN1; SMN2MAOBSMPD1 | |
| SCHEMBL12772071 | 0.68 | MAOB (0.62) | NPC1RAB9AHPGDSMN1; SMN2MAOB | |
| SCHEMBL3056405 | 0.68 | MAOA (0.62) | CHRNA7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7827220 | 0.68 | PDGFRB (0.59) | CHRNA7CTSLSRD5A1SRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433124-B | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-115433124-A | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115433124-B | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115433124-B | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115433124-A | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433124-A | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |