SCHEMBL454245

SCHEMBL454245

O=C(O)CN1CCCN(CC(=O)O)CCN(CC(=O)O)CCCN(CC(=O)O)CC1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.56
GAA P10253 1/20 0.46
ALDH1A1 P00352 4/20 0.43
SLC6A9 P48067 1/20 0.43
CYP1A2 P05177 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SIGMAR1 Q99720 2/20 0.39
S1PR1 P21453 1/20 0.38
HTT P42858 1/20 0.38
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893723 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL3504659 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL1065178 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL21454626 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL321552 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL336249 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL17512849 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL21320722 0.97 HSD17B10 (0.54) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL1661688 0.97
SCHEMBL661575 0.97 HSD17B10 (0.58) HSD17B10GAAALDH1A1SLC6A9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP claimed
EP-3986465-B1 SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS MAX PLANCK GESELLSCHAFT (DE) 2026-05-13 EP claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US claimed
US-20260108637-A1 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM UNIV JOHNS HOPKINS (US) 2026-04-23 US claimed
EP-4727561-A1 TREATMENT OF SOLID TUMORS WITH A REGIMEN OF TARGETED RADIONUCLIDE THERAPY AND GENETICALLY ENGINEERED IMMUNE CELL THERAPIES Wisconsin Alumni Research Foundation (US) 2026-04-22 EP claimed
EP-4719494-A2 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM The Johns Hopkins University (US) 2026-04-08 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4713029-A1 MODIFIED CELL, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING A MODIFIED CELL Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (DE) 2026-03-25 EP claimed
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix CASE WESTERN RESERVE UNIVERSITY (US) 2026-03-17 US claimed
US-20030060382-A1 Solution composition for removing a remaining photoresist resin HYNIX SEMICONDUCTOR INC. (KR) 2003-03-27 US claimed
WO-2002067859-A3 ASCORBIC ACID ANALOGS FOR METALLORADIOPHARMACEUTICALS BRISTOL MYERS SQUIBB PHARMA CO (US) 2002-11-28 WO claimed
US-20020122769-A1 Ascorbic acid analogs for metalloradiopharmaceuticals LANTHEUS MEDICAL IMAGING, INC. 2002-09-05 US claimed
EP-0766968-B1 Diagnostic imaging agent NIHON MEDIPHYSICS CO LTD (JP) 2001-01-17 EP claimed
US-6030840-A CONTACTING CHELATED LANTHANIDE METAL IONS BOUND TO MARKER WITH BUFFERED SOLUTION OF DETERGENT, ENHANCER REAGENT AND POLYANION; IONS DISSOCIATE FROM MARKER AND REASSOCIATE WITH ENHANCER; THEN DETERMINING AMOUNT OF IONS LIBERATED NEN LIFE SCIENCES, INC. (US) 2000-02-29 US claimed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO claimed
US-5863518-A BIFUNCTIONAL POLYAMINOPOLYCARBOXYLIC ACID LIGAND IS BONDED TO AMINO OLIGOSACCHARIDE COMPOSED OF 3 TO 6 MONOSACCHARIDE AND HAVING A REDUCING END OF SUGAR CHAIN, OR AN ALDEHYDE GROUP OF SUGAR CHAIN, AND COORDINATED TO METAL ION NIHON MEDI-PHYSICS CO., LTD. (JP) 1999-01-26 US claimed
EP-0766968-A1 Diagnostic imaging agent NIHON MEDI-PHYSICS CO., LTD. (JP) 1997-04-09 EP claimed
EP-0709100-A1 Contrast agent, containing several detection groups per molecule NIHON MEDI-PHYSICS CO., LTD. (JP) 1996-05-01 EP claimed
EP-0707857-A1 Chitosan oligomer derivatives, labelled with Gd-DTPA, for use as magnetic resonance contrast agents NIHON MEDI-PHYSICS CO., LTD. (JP) 1996-04-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 HSD17B10 4795/4885GAA 1158/4885ALDH1A1 4698/4885
US-20020122769-A1 Ascorbic acid analogs for metalloradiopharmaceuticals SLC40A1, TTPA, SLC39A14 HSD17B10 3734/4885GAA 325/4885ALDH1A1 222/4885
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix FN1, INHA, EDNRB HSD17B10 4785/4885GAA 2461/4885ALDH1A1 4553/4885
US-20260108637-A1 USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM MUSK, TNNC1, TNNI3 HSD17B10 4069/4885GAA 1395/4885ALDH1A1 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.