Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 18/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506233 | 0.92 | GPR52 (0.81) | GPR52S1PR4S1PR5 | |
| SCHEMBL13505677 | 0.85 | GPR52 (0.77) | GPR52S1PR4S1PR5 | |
| SCHEMBL13505915 | 0.84 | GPR52 (0.76) | GPR52S1PR4S1PR5 | |
| SCHEMBL6864741 | 0.83 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864122 | 0.81 | GPR52 (0.66) | GPR52 | |
| SCHEMBL1848342 | 0.79 | GPR52 (0.73) | GPR52 | |
| SCHEMBL6865069 | 0.79 | GPR52 (0.65) | GPR52 | |
| SCHEMBL1855122 | 0.78 | GPR52 (0.69) | GPR52S1PR4S1PR5 | |
| SCHEMBL6864259 | 0.78 | GPR52 (0.66) | GPR52 | |
| SCHEMBL13506797 | 0.78 | GPR52 (0.66) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |