SCHEMBL68653

SCHEMBL68653

Oc1ccc(Cc2ccccc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 1.00
HSPA5 P11021 1/20 0.65
ALOX5 P09917 2/20 0.59
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
BCL2 P10415 1/20 0.50
BCL2L1 Q07817 1/20 0.50
IDO1 P14902 2/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
THRB P10828 1/20 0.47
ALOX12 P18054 1/20 0.47
HIF1A Q16665 2/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506902 1.00 KEAP1 (1.00) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL920838 0.98 KEAP1 (0.96) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL16242571 0.94 KEAP1 (0.88) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL9776607 0.93 KEAP1 (0.86) KEAP1HSPA5ALOX5MEN1KMT2A
SCHEMBL30616875 0.93 KEAP1 (0.86) KEAP1HSPA5ALOX5MEN1KMT2A
SCHEMBL12589848 0.92 KEAP1 (0.85) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL22240444 0.90 KEAP1 (0.81) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL8656644 0.88 KEAP1 (0.78) KEAP1HSPA5ALOX5ESR1ESR2
SCHEMBL8925742 0.86 KEAP1 (0.76) KEAP1HSPA5ALOX5MEN1KMT2A
SCHEMBL30335116 0.86 KEAP1 (0.75) KEAP1HSPA5ALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2559 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594390-A1 TWO-COMPONENT COMPOSITION BASED ON EPOXY RESIN Bostik SA (FR) 2025-08-06 EP claimed
CN-119998266-A Process for producing benzoxazine compound 本州化学工业株式会社 2025-05-13 CN claimed
WO-2024106525-A1 METHOD FOR PRODUCING BENZOXAZINE COMPOUND 本州化学工業株式会社 2024-05-23 WO claimed
WO-2024069085-A1 TWO-COMPONENT COMPOSITION BASED ON EPOXY RESIN BOSTIK SA (FR) 2024-04-04 WO claimed
CN-117182794-A Thin wheel with glass reinforcement 圣戈班磨料磨具有限公司 2023-12-08 CN claimed
CN-113485072-B Photoresist composition and application thereof 北京科华微电子材料有限公司 2023-11-07 CN claimed
CN-114031736-B Modified phenolic resin for photoresist, preparation method thereof and photoresist composition 广东粤港澳大湾区黄埔材料研究院 2023-10-10 CN claimed
CN-113845656-B Composition for preparing glass-like body, preparation method and application thereof 江苏富琪森新材料有限公司 2023-09-15 CN claimed
CN-116124959-A Method for detecting bis- (hydroxyphenyl) methane component for polymer 山东海科创新研究院有限公司 2023-05-16 CN claimed
US-20230110767-A1 METHOD FOR PREPARING A SOLID FORM OF BISPHENOL F ADITYA BIRLA CHEMICALS (THAILAND) LTD. (ADVANCED MATERIALS) (TH) 2023-04-13 US claimed
EP-0626425-A2 Compatible thermoplastic compositions based on polyesters and polycarbonates ENICHEM S.p.A. (IT) 1994-11-30 EP claimed
US-5045626-A 2,7-Naphthalenedicarboxylate SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1991-09-03 US claimed
US-4463163-A Polycarbonate from 4,4'-bis (4-hydroxyphenyl thio)biphenyls MOBAY CHEMICAL CORPORATION (US) 1984-07-31 US claimed
US-4338470-A FREE-FLOWING, STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1982-07-06 US claimed
US-4110314-A Process for preparing an aromatic polymer in the presence of an inert nonpolar aromatic reaction lubricant DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1978-08-29 US claimed
US-4060504-A Emulsifiable resoles having dispersed inert salts MONSANTO COMPANY (US) 1977-11-29 US claimed
US-4028367-A REACTING PHENOL WITH FORMALDEHYDE, DIHYDROXYDIPHENYLMETHANES PRESENT TO INHIBIT CRYSTAL FORMATION MONSANTO COMPANY (US) 1977-06-07 US claimed
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US claimed
US-3956205-A High efficiency aqueous resole solutions being stable to crystallization and emulsifiable with method of manufacture MONSANTO COMPANY (US) 1976-05-11 US claimed
US-3956204-A RESOLES MONSANTO COMPANY (US) 1976-05-11 US claimed