SCHEMBL6865337

SCHEMBL6865337

N#Cc1ccc(C#Cc2cc[c]c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
KIF11 P52732 2/20 0.34
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
FFAR1 O14842 1/20 0.33
PTGS1 P23219 1/20 0.33
TSHR P16473 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.31
MMP3 P08254 1/20 0.31
ENPP2 Q13822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184366 0.86
SCHEMBL10435213 0.78 KIF11 (0.49) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL241059 0.75 CA2 (0.46) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL1419178 0.75 CYP1A1 (0.35)
SCHEMBL920014 0.74 PARP15 (0.42) CA2CA9KDM4EFFAR1
SCHEMBL5607030 0.72 CA2 (0.58) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL10300311 0.72 CA2 (0.58) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL15934230 0.71 KDM4E (0.57) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL31590251 0.70 CA2 (0.57) CYP2A6ALDH1A1CA12CA2CA3
SCHEMBL1419567 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6805920-B2 For producing liquid crystal display (LCD) NITTO DENKO CORPORATION (JP) 2004-10-19 US disclosed