SCHEMBL6865407

SCHEMBL6865407

C=C1C(=O)CCCC1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.34
OAT P04181 1/20 0.33
SIRT1 Q96EB6 2/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021751 0.87 GABRP (0.30)
SCHEMBL596950 0.87 GABRP (0.30)
SCHEMBL863518 0.87 GABRP (0.30)
SCHEMBL1835404 0.78 MCL1 (0.36) MCL1OATSIRT1KDM4EPOLB
SCHEMBL6622419 0.76
Ethylene SCHEMBL10582422 0.74 MCL1 (0.48) MCL1OATSIRT1KDM4EPOLB
SCHEMBL932332 0.73
SCHEMBL22468834 0.73
SCHEMBL28564648 0.71
Ethane SCHEMBL4051846 0.70 MCL1 (0.48) MCL1SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999204-B1 NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION NIPPON KAYAKU KK (JP) 2004-10-13 EP disclosed
US-6384063-B1 Compound having effect of promoting neuron differentiation NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2002-05-07 US disclosed
CN-1268937-A Novel compound having effect of promoting neuron differentiation NIPPON KAYAKU KK (JP) 2000-10-04 CN disclosed
EP-0999204-A1 NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION Nippon Kayaku Kabushiki Kaisha (JP) 2000-05-10 EP disclosed