SCHEMBL1835404

SCHEMBL1835404

O=C1CCCC(C(=O)O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.36
SIRT1 Q96EB6 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
OAT P04181 1/20 0.31
PTK2 Q05397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15657471 0.80 MKNK1 (0.32) MCL1PTK2
SCHEMBL6865407 0.78 MCL1 (0.34) MCL1SIRT1KDM4EPOLBL3MBTL1
SCHEMBL7076676 0.78 ELANE (0.33) MCL1
SCHEMBL134765 0.77 MCL1 (0.62) MCL1KDM4EPOLBL3MBTL1
SCHEMBL22468834 0.76
SCHEMBL932332 0.76
SCHEMBL29459692 0.76 SIRT1 (0.33) MCL1SIRT1KDM4EPOLBL3MBTL1
SCHEMBL15475264 0.75 THRB (0.38) KDM4EL3MBTL1
SCHEMBL10827651 0.75 GLI1 (0.34)
Ethylene SCHEMBL10582422 0.73 MCL1 (0.48) MCL1SIRT1KDM4EPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513401-B1 METHOD FOR INHIBITING DIFFERENTIATION AND FORMATION OF CONIFEROPHYTA MALE FLOWER BY TREATMENT WITH PROHEXADIONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2011-05-11 EP claimed
US-20080153705-A1 METHOD FOR INHIBITING DIFFERENTITATION AND FORMATION OF CONIFEROPHYTA MALE FLOWERS BY TREATMENT WITH PROHEXADIONE COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2008-06-26 US claimed
EP-1513401-A4 METHOD FOR INHIBITING DIFFERENTIATION AND FORMATION OF CONIFEROPHYTA MALE FLOWER BY TREATMENT WITH PROHEXADIONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2005-06-22 EP claimed
US-20050119131-A1 Method for inhibiting differentiation and formation of coniferophyta male flower by treatment with prohexadione compounds SYNGENTA CROP PROTECTION, INC. 2005-06-02 US claimed
EP-1513401-A2 METHOD FOR INHIBITING DIFFERENTIATION AND FORMATION OF CONIFEROPHYTA MALE FLOWER BY TREATMENT WITH PROHEXADIONE COMPOUNDS Syngenta Participations AG (CH) 2005-03-16 EP claimed
WO-2003084323-A2 METHOD FOR INHIBITING DIFFERENTIATION AND FORMATION OF CONIFEROPHYTA MALE FLOWER BY TREATMENT WITH PROHEXADIONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2003-10-16 WO claimed
EP-0338986-B1 PLANT GROWTH INHIBITING AGENT CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
EP-0224441-B1 PLANT GROWTH REGULATING AGENTS CIBA-GEIGY AG (CH) 1990-06-20 EP claimed
EP-0126713-B1 CYCLOHEXANEDIONE-CARBOXYLIC-ACID DERIVATIVES HAVING A HERBICIDAL AND PLANT GROWTH REGULATING ACTIVITY CIBA-GEIGY AG (CH) 1989-01-18 EP claimed
US-4693745-A Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1987-09-15 US claimed
US-4623382-A PRE- AND POSTEMERGENCE CIBA-GEIGY CORPORATION (US) 1986-11-18 US claimed
US-4618360-A Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1986-10-21 US claimed
US-4584013-A Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1986-04-22 US claimed
EP-0028445-B1 ACRIDINONES, THEIR PREPARATION AND USE; INTERMEDIATES AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1985-10-23 EP claimed
US-20260053138-A1 TRINEXAPAC-ETHYL FORMULATIONS Adama Australia Pty Ltd (AU) 2026-02-26 US disclosed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
CN-104478707-A Preparation method of prohexadione calcium UNIV JIANGXI AGRICULTURAL 2015-04-01 CN disclosed
US-4584013-A Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1986-04-22 US disclosed
US-4584013-A Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1986-04-22 US disclosed
EP-0126713-A2 Cyclohexanedione-carboxylic-acid derivatives having a herbicidal and plant growth regulating activity CIBA-GEIGY AG (CH) 1984-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153705-A1 METHOD FOR INHIBITING DIFFERENTITATION AND FORMATION OF CONIFEROPHYTA MALE FLOWERS BY TREATMENT WITH PROHEXADIONE COMPOUNDS CYP17A1, CYP21A2, CYP51A1 MCL1 948/4885SIRT1 880/4885KDM4E 4322/4885
US-20260053138-A1 TRINEXAPAC-ETHYL FORMULATIONS LIPC, TRRAP, LIPE MCL1 3588/4885SIRT1 1051/4885KDM4E 352/4885
US-20050119131-A1 Method for inhibiting differentiation and formation of coniferophyta male flower by treatment with prohexadione compounds CYP17A1, CYP51A1, CYP21A2 MCL1 2094/4885SIRT1 870/4885KDM4E 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.