Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072974 | 0.80 | SRC (0.48) | POLBALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL778325 | 0.74 | HTT (0.40) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13025222 | 0.71 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28577206 | 0.71 | ALDH1A1 (0.41) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3136274 | 0.69 | MME (0.38) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3139482 | 0.67 | ALDH1A1 (0.41) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10774890 | 0.67 | HDAC3 (0.37) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29065729 | 0.66 | IDO1 (0.39) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30546653 | 0.66 | EPHX2 (0.45) | HTTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL11212250 | 0.65 | SRC (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812342-B2 | DIFFUSE ACROSS CELL MEMBRANES OF FULLY INTACT CELLS AND REGENERATE THEIR PARENT MOLECULES BY CELLULAR ESTERASE HYDROLYSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-11-02 | — | — | US | claimed |