Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292702 | 0.90 | MAPT (0.67) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL24218456 | 0.84 | KDM4E (0.68) | MAPTKMT2APKMALOX5KDM4E | |
| SCHEMBL11369720 | 0.83 | KDM4E (0.63) | MAPTKMT2APKMALDH1A1KDM4E | |
| SCHEMBL19360824 | 0.83 | MAPT (0.59) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL19360854 | 0.83 | ALOX5 (0.67) | MAPTKMT2APKMALOX5KDM4E | |
| SCHEMBL19360021 | 0.83 | MAPT (0.59) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL27690202 | 0.83 | MAPT (0.59) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL11482833 | 0.82 | KMT2A (0.72) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL527544 | 0.82 | KMT2A (0.71) | MAPTKMT2APKMALOX5ALDH1A1 | |
| SCHEMBL10398771 | 0.80 | MAPT (0.43) | MAPTKMT2APKMALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809206-B2 | CONTACTING A PHENYL ESTER COMPOUND WITH A CYCLIC COMPOUND IN THE PRESENCE OF A SOURCE OF CYANIDE OR FLUORIDE TO PREPARE ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-10-26 | — | — | US | disclosed |
| US-20030232984-A1 | Method for acylating cyclic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-18 | — | — | US | disclosed |
| US-20020049317-A1 | Method for acylating cyclic compounds | E.I. DU PONT DE NEMOURS AND COMPANY | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049317-A1 | Method for acylating cyclic compounds | LCAT, ACOT7, AGPAT5 | MAPT 4261/4885KMT2A 1389/4885PKM 2242/4885 |
| US-20030232984-A1 | Method for acylating cyclic compounds | LCAT, ACOT7, AGPAT5 | MAPT 4261/4885KMT2A 1389/4885PKM 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.