SCHEMBL527544

SCHEMBL527544

O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
PKM P14618 1/20 0.71
ALOX5 P09917 3/20 0.69
MAPT P10636 5/20 0.68
HGFAC Q04756 1/20 0.62
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
ALDH1A1 P00352 3/20 0.60
SMN1; SMN2 Q16637 1/20 0.57
GAA P10253 3/20 0.57
KDM4E B2RXH2 2/20 0.57
HPGD P15428 1/20 0.57
PARP10 Q53GL7 1/20 0.57
HTT P42858 1/20 0.56
RAB9A P51151 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NR1H4 Q96RI1 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333093 0.95 KMT2A (0.66) KMT2APKMALOX5MAPTHGFAC
P-Nitrophenol SCHEMBL7158777 0.94 KMT2A (0.64) KMT2APKMALOX5MAPTHGFAC
SCHEMBL5973956 0.93 ALOX5 (0.73) KMT2APKMALOX5MAPTHGFAC
SCHEMBL12649366 0.92 ALOX5 (0.68) KMT2APKMALOX5MAPTHGFAC
Guanidine SCHEMBL3748808 0.92 KMT2A (0.67) KMT2APKMALOX5MAPTHGFAC
SCHEMBL4951809 0.91 KMT2A (0.84) KMT2APKMALOX5MAPTHGFAC
SCHEMBL18434657 0.91 KMT2A (0.84) KMT2APKMALOX5MAPTHGFAC
SCHEMBL542043 0.91 KMT2A (0.84) KMT2APKMALOX5MAPTHGFAC
SCHEMBL10636579 0.91 KMT2A (0.84) KMT2APKMALOX5MAPTHGFAC
SCHEMBL6032592 0.91 KMT2A (0.68) KMT2APKMALOX5MAPTHGFAC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118207152-A Culture solution capable of promoting growth and improving functions of vascular endothelial stem cells 张易 2024-06-18 CN claimed
CN-116904029-A Preparation method of cross-linked sulfonated polyimide film 西南科技大学 2023-10-20 CN claimed
CN-111393695-B Preparation method of self-crosslinking sulfonated polyimide membrane 西南科技大学 2022-08-12 CN claimed
CN-114591249-A Side chain type sulfonated aromatic diamine with ether bond and preparation method thereof 中国石化扬子石油化工有限公司 2022-06-07 CN claimed
CN-111393643-A Positive photosensitive polyimide resin and preparation method thereof 艾森半导体材料(南通)有限公司 2020-07-10 CN claimed
CN-111393695-A Preparation method of self-crosslinking sulfonated polyimide membrane 西南科技大学 2020-07-10 CN claimed
US-9656927-B2 Process for the synthesis of carboxylic acid derivatives COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-23 US claimed
US-20160272554-A1 PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-09-22 US claimed
WO-2015063798-A1 A PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-05-07 WO claimed
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
JP-61211088-A None JP disclosed
US-20260060992-A1 COMPOSITIONS FOR OVERCOMING TETRACYCLINE ANTIBIOTIC RESISTANCE AND METHODS OF USE THEREOF WASHINGTON UNIVERSITY (US) 2026-03-05 US disclosed
WO-2024259930-A9 PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF 润佳(苏州)医药科技有限公司 2025-04-24 WO disclosed
WO-2024259930-A1 PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF 润佳(苏州)医药科技有限公司 2024-12-26 WO disclosed
CN-112625028-B Compounds and compositions for inhibiting SHP2 activity 诺华股份有限公司 2024-10-29 CN disclosed
US-4642352-A 7-ACYLAMINO-9A-METHOXY DERIVATIVES; ANIMAL ANTITUMOR AGENTS BRISTOL-MYERS COMPANY (US) 1987-02-10 US disclosed
JP-S61211088-A THERMAL RECORDING MATERIAL RICOH CO LTD 1986-09-19 JP disclosed
US-4061851-A 7-Amino-7-arylthio cephalosporins E. R. SQUIBB & SONS, INC. (US) 1977-12-06 US disclosed
US-4026886-A 7-Acyl-7-arylthiocephalosporins E. R. SQUIBB & SONS, INC. (US) 1977-05-31 US disclosed
US-3954744-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272554-A1 PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES PCCA, CPS1, CS KMT2A 1512/4885PKM 1342/4885ALOX5 1006/4885
US-20260060992-A1 COMPOSITIONS FOR OVERCOMING TETRACYCLINE ANTIBIOTIC RESISTANCE AND METHODS OF USE THEREOF TRMT1, SLC11A2, NOP2 KMT2A 1161/4885PKM 3534/4885ALOX5 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.