SCHEMBL6865765

SCHEMBL6865765

Cc1ccccc1C(=O)Oc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
MAPT P10636 2/20 0.59
MEN1 O00255 2/20 0.55
LMNA P02545 2/20 0.55
MYC P01106 1/20 0.51
NPC1 O15118 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 1/20 0.48
PDCD1 Q15116 3/20 0.46
CD274 Q9NZQ7 3/20 0.46
MCL1 Q07820 1/20 0.46
POLB P06746 1/20 0.45
HSD17B10 Q99714 2/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6865768 0.86 KMT2A (0.54) KMT2AMAPTMEN1LMNAMYC
SCHEMBL28383281 0.84 KMT2A (0.53) KMT2AMAPTMEN1LMNANPC1
SCHEMBL6870291 0.83 PARP10 (0.54) KMT2AMAPTMEN1LMNANPC1
SCHEMBL6868696 0.83 NPC1 (0.53) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1254116 0.82 KMT2A (0.64) KMT2AMAPTMEN1LMNANPC1
SCHEMBL9299818 0.81 HSD17B10 (0.57) MAPTLMNANPC1CYP1A2CYP2C9
SCHEMBL14062702 0.79 KMT2A (0.65) KMT2AMAPTMEN1LMNANPC1
SCHEMBL6885269 0.79 KDM4E (0.58) KMT2AMAPTMEN1LMNAMYC
SCHEMBL269580 0.78 SMN1; SMN2 (0.70) MAPTLMNANPC1CYP1A2CYP2C9
Trimethylammonium SCHEMBL60750 0.78 KMT2A (0.59) KMT2AMAPTMEN1LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed