SCHEMBL6865768

SCHEMBL6865768

Cc1ccccc1C(=O)Oc1ccc(C(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
NPC1 O15118 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
MAPT P10636 3/20 0.49
LMNA P02545 1/20 0.49
PDCD1 Q15116 8/20 0.47
CD274 Q9NZQ7 8/20 0.47
MYC P01106 1/20 0.45
HTT P42858 1/20 0.44
EPHX1 P07099 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
RAB9A P51151 1/20 0.43
BACE1 P56817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6865765 0.86 KMT2A (0.59) KMT2AMEN1NPC1CASP3SENP8
SCHEMBL6870295 0.82 KMT2A (0.57) KMT2AMEN1MAPTRAB9A
SCHEMBL6868699 0.82 KMT2A (0.47) KMT2AMEN1NPC1MAPTLMNA
SCHEMBL10479949 0.81 BACE1 (0.64) KMT2AMEN1NPC1MAPTLMNA
SCHEMBL10526606 0.79 MAPT (0.53) KMT2AMEN1NPC1MAPTLMNA
SCHEMBL6701301 0.77 SMN1; SMN2 (0.63) LMNAHTTCYP1A2CYP2C19BACE1
SCHEMBL11686000 0.77 POLB (0.54) KMT2AMEN1BACE1
SCHEMBL11663752 0.77 KMT2A (0.63) KMT2AMEN1NPC1CASP3SENP8
SCHEMBL1254116 0.77 KMT2A (0.64) KMT2AMEN1NPC1CASP3SENP8
SCHEMBL1945679 0.76 ELANE (0.52) KMT2AMEN1NPC1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed