Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865895 | 0.86 | CREBBP (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9680841 | 0.85 | SMN1; SMN2 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4213761 | 0.84 | MGLL (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5150372 | 0.82 | KDM4E (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16491070 | 0.81 | EGFR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6872463 | 0.80 | CREBBP (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15662814 | 0.80 | MGLL (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL68346 | 0.78 | MGLL (0.53) | MAPTKDM4EL3MBTL1RAB9ATDP1 | |
| SCHEMBL3195430 | 0.78 | MAPT (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9544375 | 0.78 | HPGD (0.63) | MAPTKDM4ESMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |