Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216700 | 0.92 | MGLL (0.62) | HPGDHSD17B10MAPTCYP1A2CYP3A4 | |
| SCHEMBL14930505 | 0.91 | SMPD1 (0.65) | HPGDHSD17B10MAPTCYP1A2CYP3A4 | |
| SCHEMBL2149738 | 0.90 | MAPT (0.66) | HPGDMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29171439 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9307505 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29171419 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29171402 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29171407 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14930509 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29171438 | 0.90 | SMPD1 (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283429-A1 | COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS | Janssen Biopharma, Inc. | 2017-10-05 | — | — | US | disclosed |
| US-9724351-B2 | Compounds for the treatment of paramoxyvirus viral infections | ALIOS BIOPHARMA, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20150238498-A1 | COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2015-08-27 | — | — | US | disclosed |
| WO-1993018045-A1 | ANTI-CANCER PYRROLOBENZODIAZEPINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238498-A1 | COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS | SARS1, MAVS, ZC3HAV1 | HPGD 2567/4885HSD17B10 3484/4885MAPT 4529/4885 |
| US-20170283429-A1 | COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS | MAVS, SARS1, ZC3HAV1 | HPGD 2844/4885HSD17B10 3992/4885MAPT 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.