Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 5/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865737 | 0.91 | TDP2 (0.51) | TDP2IDO1ALDH1A1LMNAMAPT | |
| SCHEMBL7043300 | 0.83 | TOP2A (0.52) | TDP2TOP2AKMT2AGAANSD2 | |
| SCHEMBL6407197 | 0.77 | TOP2A (0.46) | TDP2TOP2AGAANSD2ABL1 | |
| SCHEMBL6409824 | 0.75 | TOP2A (0.57) | TDP2TOP2AALDH1A1KMT2AGAA | |
| SCHEMBL6408548 | 0.74 | TOP2A (0.53) | TDP2TOP2ALMNAMAPTMAPK1 | |
| Iodide SCHEMBL6867075 | 0.74 | TOP2A (0.56) | TDP2TOP2AALDH1A1KMT2AGAA | |
| SCHEMBL6863937 | 0.74 | TOP2A (0.50) | TDP2TOP2ALMNAMAPTMAPK1 | |
| SCHEMBL7040428 | 0.73 | MEN1 (0.42) | TDP2TOP2AKMT2AGAANSD2 | |
| SCHEMBL6412880 | 0.72 | TOP2A (0.57) | TDP2TOP2AALDH1A1KMT2AGAA | |
| SCHEMBL6867428 | 0.72 | TOP2A (0.57) | TDP2TOP2AALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |