Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043300 | 0.90 | TOP2A (0.52) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6865737 | 0.83 | TDP2 (0.51) | TDP2GAA | |
| SCHEMBL6411062 | 0.81 | MEN1 (0.47) | MEN1THRBBLMKMT2ATDP1 | |
| Iodide SCHEMBL6859932 | 0.80 | MEN1 (0.46) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6407858 | 0.78 | TDP2 (0.39) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6411071 | 0.78 | S100A4 (0.49) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6865755 | 0.78 | MEN1 (0.47) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6408357 | 0.77 | MEN1 (0.44) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6409081 | 0.77 | HKDC1 (0.46) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL6866332 | 0.75 | MEN1 (0.44) | MEN1THRBBLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |