SCHEMBL6866347

SCHEMBL6866347

C=CCOC(C=C[Si](C)(C)C)OCC=C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6866346 1.00 MEN1 (0.36) MEN1KMT2A
SCHEMBL8358978 0.75 MEN1 (0.34) MEN1KMT2A
SCHEMBL8358982 0.75 MEN1 (0.34) MEN1KMT2A
SCHEMBL11322497 0.71 MEN1 (0.36) MEN1KMT2A
SCHEMBL2048729 0.68 CA1 (0.32) MEN1KMT2A
SCHEMBL12971552 0.64 CA1 (0.30)
SCHEMBL7076488 0.64 CA1 (0.30)
SCHEMBL206514 0.64
SCHEMBL159503 0.63 LMNA (0.40) MEN1KMT2A
SCHEMBL466023 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116448-A1 Substances for the therapy of diseases caused by highly proliferating cells HANS-GUENTHER SCHMALZ (DE) 2004-06-17 US disclosed